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GSH depletion triggers cell cycle arrest in G1/S checkpoint and induces SIPS SIPS is well-characterized in cells treated with exogenous oxidants such as tBH and H 2 O 2 10,11
Interestingly, we found that CPT1 is a downstream protein of AMPK, and inhibition of AMPK expression leads to a decrease in the level of CPT1
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MAT is a quinolizidine-rich natural alkaloid with diverse biological effects, including anti-inflammatory, antifibrotic, antiviral, and analgesic properties ( , GPX4, and Ferritin, and decreased the expression of CD71, ACSL4, and POR