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Self healing hydrogels composed of amyloid nano fibrils for cell culture and stem cell differentiation
While Nrf2 and JAK2/STAT3 are indeed activated as protective responses during MIRI, the overwhelming and dynamic nature of the oxidative insult often impairs their full protective capacity or overwhelms the defense mechanisms they regulate, leading to a functional failure in restoring redox balance
Elevated lipid ROS and neutrophil ferroptosis have been observed in the serum of systemic lupus erythematosus (SLE) patients (115), yet there have been no reports on neutrophil ferroptosis in CVDs
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(2021) 118(45):e2100050118
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