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The SURMOUNT-5 clinical trial published in The New England Journal of Medicine showed that Zepbound (tirzepatide) achieved an average weight loss of 20.2% compared to 13.7% with Wegovy (semaglutide) at 72 weeks

Rohm TV, Meier DT, Olefsky JM, Donath MY (2022) Inflammation in obesity, diabetes and related Disorders

Together with other changes that we have found, this might be a reason for the improved resistance of the old rat heart to I/R that we observed

This double action is why some people notice their skin becoming lighter and more even-toned over time

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