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959 tFNA-Cur can enhance mitochondrial function by activating the Nrf2/GPX4 pathway in vitro and in vivo, inhibit ferroptosis of BMSCs, promote osteogenic differentiation of BMSCs under a high glucose microenvironment, and promote bone formation

Those interested in berberine should discuss its use with their healthcare provider, particularly if they have diabetes, take other medications, or have cardiovascular disease, as professional guidance can help integrate supplements safely within an overall treatment plan while maintaining appropriate monitoring and medication management

Escalation schedule Follow-up frequency Additional support needed

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Outer-sphere electron-transfer reactions of ascorbate anions

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