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Common early side effects include mild nausea, constipation, or fatigue, which generally diminish as your body adjusts

When Rybelsus is taken with other drugs, it can change how they work or make some side effects more likely or severe

Ruggeri RM, Minciullo P, Saitta S, Giovinazzo S, Certo R, Campenn A, Benvenga, S

(3) outcomes: all clinical outcomes, such as cardiovascular event, death, changing in glycosylated hemoglobin type A1C (HbA1c), body weight, fasting plasma glucose (FPG) and safety outcomes

The medication is contraindicated for individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

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