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Regeneration of oxidized form of glutathione to its reduced form depends on availability of NADPH and ATP in neuronal system
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This selective synaptic disruption predominantly affects low-spontaneous-rate, high-threshold auditory nerve fibers, effectively silencing a subset of the afferent input 17
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Once activated by phosphorylation (pCREB), it initiates the transcription of brain derived neurotrophic factor (BDNF) which is responsible for memory formation and synaptic plasticity (Amidfar et al
Additionally, reduced food intake and overall caloric deficit may lower energy levels and mood, which can further contribute to a short-term drop in sexual interest
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