Protein aggregates can potentially trigger immune responses, since the immune system may recognize aggregated forms of a peptide as foreign even when it tolerates the properly folded monomer
Given how long tirzepatide has taken to get PBS consideration for weight loss, expect a significant wait after TGA approval before PBS listing
The next step is a medically supervised detox, which often includes glutathione supplementation to raise the level of GSH, along with dietary modifications, antifungals to kill the mold in the body, and other supplements to sequester and flush the toxic soup from the system
Approximately 87.8% of the reports were derived from North America, which may be attributed to FAERS being established in the United States
In June 2025, the European Medicines Agency officially recognized NAION as a very rare side effect of semaglutide after reviewing all data, concluding it may affect up to 1 in 10,000 people and recommending product information updates
Elevated liver enzymes usually indicate inflammation or injury of the liver
