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Overactivity of the sympathetic nervous system is more significant in obese subjects with type 2 diabetes than in those subjects without diabetes (118)

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As of the 28 January 2025 revision it is indicated not only for glycaemic control in type 2 diabetes, but also to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease, and to reduce the risk of sustained eGFR decline, end-stage kidney disease and cardiovascular death in adults with type 2 diabetes and chronic kidney disease

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Cancer Res (2021) 81:38499