It remains in the injected area and may add temporary volume , but this is localized and not reflective of systemic weight gain
In healthy adults the total concentration sits around 200 to 600 pmol/L, but the upper reference limit varies by laboratory and by analytical platform
251 In cancer, Notch signaling exhibits context-dependent and often paradoxical roles, contributing to tumor progression, cancer stemness, immune evasion, and therapy resistance
Mol Neurodegenerat (2019) 14(1)
Li J, Zhang X, Wang M, Li X, Mu H, Wang A, et al
Reported EC values in transfected cell assays sit in the sub-nanomolar to low-nanomolar range at MC1R and MC4R, with roughly an order of magnitude lower potency at MC3R and MC5R, and it is essentially inactive at MC2R, the adrenocorticotropin receptor