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Briefly, 0.5% mixed-stage parasites were incubated with the compounds of interest in black 96-well plates with a translucent bottom (Falcon) for 72 hours under a hypoxic atmosphere

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On this basis, we summarize the connections and differences of different E3 ubiquitin ligases in the pathogenesis, and elaborate on the regulatory progress of different DUBs on the pathogenesis of PD

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