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Bariatric surgery consultation should be considered for patients with BMI 35 kg/m with obesity-related complications or 40 kg/m without complications (per ASMBS/IFSO 2022 guidelines), though insurance coverage in the US often requires BMI 35 kg/m with comorbidities or 40 kg/m without

The 2.5 mg dosage is for treatment initiation and is not intended for glycemic control

For women whose GLP-1 therapy is partly motivated by cardiovascular risk reduction, this distinction is not trivial

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The role of hypothalamic estrogen receptors in metabolic regulation

however, individual prescribers and pharmacies are