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While the FDA approved semaglutide for diabetes treatment, physicians increasingly prescribe it off-label for weight management in people without diabetesa practice supported by major clinical trials and real-world outcomes
Most meaningful BMI changes occur when treatment lasts at least 1216 weeks, with the most significant improvements seen over 612 months
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Constipation from slower gastric transit
Research has explored its influence on growth hormone signaling pathways, with interest in its receptor specificity and minimal activity at other endocrine receptors when examined under controlled laboratory conditions
You should not stop semaglutide without discussing a maintenance plan with your provider
