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In SURMOUNT-1, 72 weeks of tirzepatide induced mean WL of 1622.5% in people without diabetes compared to 2.4% with placebo, with no sign of the weight plateauing, suggesting that there may be further WL with long-term use [46]
Retatrutides half-life is about 6 days, so the drug washes out over roughly 30 days from the last dose
Does Tirzepatide Burn Fat
(2) Graf MV, Kastin AJ
They are a supportive tool, not a standalone weight loss solution
This combination can enhance overall metabolic support during fat loss phases
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