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Tambasco et al

While pioneering GLP-1 drugs target a single hormone pathway, and Lillys own approved tirzepatide portfolio targets two, retatrutide is a triple agonist. It simultaneously activates three distinct hormone receptors: GLP-1, GIP, and glucagon, making it a first-in-class therapeutic

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While some consider tan temporary, leaving it untreated can lead to uneven tone, dark patches, and premature aging

With an extended half-life and enhanced bioavailability, it remains active in the body longer, ensuring prolonged effects (1)

Data are presented as the mean SD of three or four biological replicates in three or four independent samples