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This initiates the production of C-terminal membrane-tethered -secretase-derived fragment C83, which, upon additional enzymatic cleavage by -secretase, increases the concentration of p3 [50]

An open-label study in patients with episodic migraine ( n = 25) assessed a PEA-containing nutraceutical (Calmux, Bioksan, Spain

Breaking this cycle requires addressing both the immune response and the barrier dysfunction simultaneously

& Vermeulen, N

This protocol focuses on the recovery period rather than standalone treatment