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These hormones play a role in regulating glucose levels by enhancing insulin production from the pancreas in response to food intake

rather, it establishes tolerability and begins appetite-suppression effects

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However, many have limitations or exclusions

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Common APIs in this subcategory include biguanides, sulfonylureas, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, and sodium-glucose co-transporter 2 (SGLT2) inhibitors