doi: 10.2337/db08-0349 26
Rybelsus is approved for type 2 diabetes, not obesity treatment under its brand label
GLP-1 Medications : Rare risks include thyroid tumors (observed in animal studies), gallbladder issues (1%-1.6% experience gallstones), and pancreatitis
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In 2025, ongoing trials are evaluating whether MEK inhibition can delay or prevent malignant transformation, or serve as a neoadjuvant strategy to shrink MPNST prior to surgery (Gross et al., 2024)