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To identify differentially expressed genes (DEGs), we used the Limma R package 40 , which enables robust differential expression analysis in microarray experiments

Most are mild to moderate, but lead some people to discontinue treatment

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Rev Endocr Metab Disord 15(3):181187 Shan Y, Tan S, Lin Y, Liao S, Zhang B, Chen X et al (2019) The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke

Discussion: In this study, we showed that blood pressure was elevated in ghrl -/- mice and that the blood pressure rhythm was abnormal

NICE guidelines (NG28) recommend monitoring HbA1c every three to six months until stable, then six-monthly in patients with type 2 diabetes