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Like other GLP-1 medications, both formulations are started at a low dose and increased gradually to help reduce side effects
While ongoing trials continue to monitor outcomes, early data indicate retatrutide outperforms previous GLP-1 medications for weight loss and blood sugar regulation
In a study of induced osteoarthritis in rats, the authors demonstrated that spermidine supplementation reduced pyroptosis and proinflammatory cytokine production and limited pathological processes in the joints (Reference Guo, Feng and Yang88)
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An J, Zhou Y, Zhang M, et al
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