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They added that more research is needed to determine causation
W.de LeeuwN.et al (2021)
Figures 1 and 2 show the normal function of GLP-1 in human health and the mechanism by how it exerts these effects[2]
Clinical Evidence on Mood Effects of GLP-1 Weight Loss Drugs The abstract provided contains no extractable clinical data, methodology, or findings that would support evidence-based commentary on neuropsychiatric or mood-related adverse effects of GLP-1 receptor agonists
It undergoes enzymatic processing from its preproglucagon peptide precursor within intestinal L-cells, ultimately giving rise to GLP-1(1-37) and peptide variants including GLP-1(7-36)
GPs cannot routinely prescribe these medications for off-label indications such as Hashimoto's management
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