Its harmless and often used in ultra-high doses
Older adults, and those on long-term medications for acid reflux, might also be at risk
Daily research amount 300 mcg 5 mg + 1 mL BAC water 6 units 5 mg + 2 mL BAC water 12 units 5 mg + 3 mL BAC water 18 units Daily research amount 500 mcg 5 mg + 1 mL BAC water 10 units 5 mg + 2 mL BAC water 20 units 5 mg + 3 mL BAC water 30 units U-100 syringes contain 100 units per milliliter
Importantly, folic acid should not be given alone before B12 deficiency is excluded or treated, as this can mask anaemia while allowing neurological damage to progress
The absence of published half-life data is a direct consequence of how early this compound is in development: it has been used as a research tool to validate an enzyme target, not as a clinical candidate with a full pharmacokinetic package
Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline