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First, a bacterial reverse mutation test (Ames test) assessed AOD9604s mutagenic potential using four histidine-dependent auxotrophic mutants of Salmonella typhimurium (TA1535, TA1537, TA98, TA100) and one tryptophan-dependent auxotrophic mutant of Escherichia coli (WP2 uvrA), using both plate incorporation and pre-incubation methods at doses of 0, 1.6, 8, 40, 200, 1,000, and 2,000 g AOD9604/plate
doi:10.1021/bi048766p
It's therefore best to stick to normal dietary intakes
(18) The study further revealed that the effects of liraglutide on osteoblast differentiation and mitochondrial function were mediated through the GLP-1 receptor (GLP1R), as blocking GLP1R or AMP-activated protein kinase (AMPK) inhibited these outcomes
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