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In addition to being an essential detoxification mechanism for structurally diverse drugs, glucuronidation also leads to a short duration of action and loss of pharmacological activity

doi: 10.1371/journal.pone.0088136 233 OlbrichK

Other studies have found that sulforaphane increased blood glutathione levels in people but this study is the first to show that glutathione was also increased in certain brain regions and this correlated with increased plasma glutathione

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Clinical trials are underway assessing drugs targeting neuronal survival and OPC differentiation into remyelinating OLs

doi: 10.1002/advs.202207216 246 ZhangPRongKGuoJCuiLKongKZhaoCet al