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Heres whats happening underneath: ACE inhibitors dilate the efferent arteriole Diuretics reduce circulating volume NSAIDs constrict the afferent arteriole What this really means is the kidney loses its ability to maintain filtration

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doi: 10.1152/ajpcell.00043.2009 43 TaylorWEBhasinSArtazaJByhowerFAzamMWillardDHet al

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Cancer Biol Ther 7(12):18751884 Wang YF, Chen CY, Chung SF, Chiou YH, Lo HR (2004) Involvement of oxidative stress and caspase activation in paclitaxel-induced apoptosis of primary effusion lymphoma cells