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Weibull distribution modeling characterized failure patterns of time-to-onset data, where the shape parameter () defined three scenarios: the upper limit of 95% confidence interval (CI) of 1 (wear-out failure: risk escalation with prolonged use) 22 (Table S4)

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Melanin Regulation Glutathione influences the enzyme tyrosinase, reducing melanin production

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Skin Brightening and Pigmentation Control Glutathione influences melanin production by inhibiting tyrosinase activity