After reviewing five eligible randomized clinical trials involving 497 total participants, the authors found that berberine and silymarin coadministration could lead to an "advantageous improvement in lipid and glucose profile" namely, it could lower total cholesterol, low-density lipoprotein ("bad") cholesterol, and triglycerides while increasing high-density lipoprotein ("good") cholesterol.43 Such impacts are why berberine may be particularly useful to people with type 2 diabetes
Science 375 (6584), 9941000
Thats the perfect trifecta
Beibei L, Lin W, Lixu P, Xin C, Pan P, Niqing F
Selenium Deficiency Risk Predicted to Increase under Future Climate Change | PNAS March 14, 2017 114 (11) 2848-2853
This can improve quality of life and increase exercise tolerance