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This is why we often suggest that the best routine includes a balance of both
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NAPQI modifications of certain proteins can alter critical cellular functions (Liebler, 2008) and NAPQI-protein adducts have been found to accumulate in hepatocytes (Jollow et al., in vivo (LeBlanc et al., Several NAPQI-protein adducts have been identified previously in mouse, rat, and human (Wendel and Cikryt, 1981
Both epidermis-specific Mll4- knockout mice and Alox12b loss-of-function mutant mice exhibited epidermal hyperproliferation, scaling, and other cutaneous manifestations similar to ichthyosis, as well as a deficiency of ALOX12b expression in the epidermis of both mice
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Plant Physiol 187(2):618631
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