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The different mechanisms of action mean side effects from each compound remain distinct and manageable independently

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Pharmacologic Implications DPP-4 inhibitors comprise a class of non-insulin anti-diabetic therapeutic interventions that enhance insulin secretion by pancreatic -cells and act by blocking the enzymatic action of DPP-4

Discussion The clinical management of patients with type 2 diabetes has to balance the potential benefits of controlling hyperglycemia on microvascular and macrovascular complications, [11] with possible side effects of treatment and possible harm from over intensive control of glycemia