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The ratio of reduced GSH to the disulfide form (GSH/GSSG) within the endoplasmic reticulum ranges from 1:1 to 4:1, whereas the overall cellular GSH/GSSG ratio ranges from 30:1 to 100:1 (Figure 2)
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Since these guidelines are preliminary, researchers should conduct initial dose-finding studies to identify the optimal range for their specific models
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A simple 4-site rotation (left abdomen right abdomen left love handle right love handle) works for most patients
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