no appetite suppression on tirzepatide Made the jump from Tirz to Reta and wow.....after a two month plateau dropped 5lb in two weeks. Seeing a number the scale I haven't seen since 2017!!!!!!! Here is a How Long Does Tirzepatide Take

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Furthermore, semaglutide had a positive effect on the hedonic aspects of food intake such as reduced cravings, increased ability to control food intake and an altered food preference (i.e., a lower liking for high-fat and non-sweet foods) (181)

This allows for a smaller, shorter needle than the one used for an intramuscular injection, such as a flu shot, which has to go deeper into the muscle and can be more painful