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Does it cause a metabolic rebound
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Patients with renal impairment require particular caution with metformin, as reduced kidney function increases the risk of lactic acidosis, a rare but serious complication
Gastrointestinal side effects observed under cotadutide effects are similar in quality but more severe than those under GLP-1RA treatment ( Animal data on a GLP-1/GIP/glucagon triple agonist show strong effects on body weight reduction, and glucose- and lipid normalization in rodents
These gastric contents can be easily refluxed and aspirated (enter the lungs) due to the non-existent gag reflex as a result of the patient being under sedation
Low-quality products may contain fillers or formulations with limited bioavailability
