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Investigations dating back to the early 1990s have explored its effects on gastrointestinal mucosal integrity, musculoskeletal tissue repair, and angiogenic signaling cascades in rodent studies

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In addition to these steps, several products are available such as artificial saliva substitutes that can help moisturize the mouth and relieve dry mouth symptoms

Regulatory concerns prompted the inclusion of pancreatitis warnings in the prescribing information for all approved GLP-1 agonists

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