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Washington, DC: National Academies Press (1998)
A 2022 study in the Journal of Cosmetic Dermatology found that subjects who applied L-ascorbic acid followed immediately by GHK-Cu experienced 40% higher transepidermal water loss (TEWL) and delayed barrier recovery compared to those who separated application by eight hours or more
C., & McNaughton, L
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No human trial has tested the combination as of June 2026
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