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J Immunol 174:40194024 Mirabello L, Yu K, Kraft P, de Vivo I, Hunter DJ, Prescott J, Wong JY, Chatterjee N, Hayes RB, Savage SA (2010) The association of telomere length and genetic variation in telomere biology genes

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Higher doses produce more total weight loss, but the proportion of that weight loss coming from fat versus lean tissue varies with dose, activity level, and protein intake during the protocol

Monitor IGF-1 levels and consult a healthcare provider

The way to protect against this is adequate protein

Although between-group differences were not statistically significant, the 10 mg group exhibited clinically meaningful improvements in HbA1c and a greater trend toward weight loss