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Metabolic conditions can also predispose patients to gout, which may manifest as acute monoarthritis during periods of weight change
However, in the context of chronic infection and cancer, persistent antigen exposure forces antigen-specific CD8 + T cells to enter a hyporesponsive state termed exhaustion [111]
2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes: developed by the task force on the management of cardiovascular disease in patients with diabetes of the European Society of Cardiology (ESC)
Around 7% of patients in clinical trials discontinued semaglutide due to severe gastrointestinal side effects
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