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Islet-intrinsic effects of CFTR mutation
When given as a medication at pharmacological doses, these effects are amplified, which is why GLP-1 drugs produce significant improvements in blood sugar control and meaningful weight loss
Over the next 48 weeks, those who stayed on semaglutide lost a further 7.9%, whereas those switched to placebo regained 6.9%
Postoperative changes Following bariatric surgery, changes in circulating GIP levels show procedure-specific variability
Activates longevity genes like FOXO3, linked to extended lifespan