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GLP-1s for Chronic Kidney Disease GLP-1s for Advanced Liver Disease In August 2025, the FDA approved Wegovy (semaglutide) to treat adults with a type of liver disease called metabolic-associated steatohepatitis (MASH) with moderate to advanced liver scarring (fibrosis), when used alongside diet and exercise
Advanced tumors often become castration-resistant and refractory to conventional androgen-deprivation therapy (ADT) 4
Semaglutide provides significant appetite reduction
Complete reversal of significant scarring takes longer and may not be achievable for everyone
Metabolic Health
Seek support from NHS weight management services or counselling if you struggle with motivation or find yourself reverting to previous eating patterns
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