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The pharmacological mechanism of tirzepatide involves simultaneous activation of both GIP and GLP-1 receptors, which are naturally occurring incretin hormones involved in glucose homeostasis and appetite regulation

T2D patients prone to cardiorenal diseases are prescribed GLP1-RA and SGLT2i therapies

Furthermore, one of the mechanisms by which L-Carnitine supplementation may reduce oxidative stress is through the preservation of mitochondrial function by enhancing catalase and superoxide, which are antioxidant enzymes (Le Borgne et al

Neither compound is cheap, and the ongoing nature of both treatments means costs accumulate over months

Phototoxic reactions are more common than photoallergic reactions