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When exposed to ROS/H 2 O 2 , Cys274/Cys276 within DnaJb5 and Cys667/Cys669 in HDAC4 could undergo oxidation, leading to the creation of disulfide bonds within the molecules that can be reduced by TRX1
doi:10.1172/JCI110155
Mortazavi, S
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There is no established human dosing , and clinical evidence remains limited
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