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Thus, blockade of hepatic portal GLP-1R signaling causes glucose intolerance in rats, suggesting that GLP-1Rs located on nerve terminals in the hepatic portal vein contribute to the incretin action of GLP-1 (Vahl et al., Rodent studies involving pharmacological manipulation of GLP-1R in the brain by intracerebroventricular (ICV) administration of agonists and antagonists demonstrate a role for brain GLP-1R signaling in the control of glucose metabolism
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Carnitine is in the middle of this process and hence very important for the health of the cardiovascular system and supporting the proper functioning of the heart
Back Villumsen, M, Schelde, AB Jimenez-Solem, E (July 2021) 'GLP-1 based therapies and disease course of inflammatory bowel disease', eClinical Medicine, 37/100979
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