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Figure 5 In Nrf2 -deficient mice, SLPI expression in the lung is significantly reduced during MAC infection, and the number of bacteria is greatly increased Next, to confirm that SLPI expression in the lung is regulated by Nrf2 during MAC infection, BALB/c Nrf2 -deficient mice were infected intranasally with MAC bacteria, and SLPI expression and bacterial load in the lungs 2 months after infection were examined

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Glutathione plays a key role in detoxification and helps maintain cellular health

It can be highly activated by various stress stimuli, where it is required for the re-folding of damaged and unfolded proteins generated under stress 43