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However, clinical data suggest that the combination of patuximab and cetuximab leads to overlapping toxicity, making the combination intolerable

Patients typically start with an initial dose of 0.25 milligrams (mg) per week, which helps minimize potential side effects as your body adapts to the medication

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Because it is a peptide, it is highly susceptible to denaturation. Denaturation is a process where the protein structure of the medication breaks down or unfolds

Choline metabolism plays a central role in macrophage activation towards both pro-inflammatory and anti-inflammatory functions ( Figure 3 )