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Initial clinical assessment should include a thorough neurological examination documenting: Sensory testing for vibration sense (using a 128 Hz tuning fork) and proprioception Assessment of gait and coordination (Romberg's test) Evaluation of reflexes and muscle tone Cognitive screening if indicated Fundoscopy if visual symptoms are present History of nitrous oxide exposure (recreational or occupational) Laboratory investigations recommended in UK practice include: Serum B12 level whilst the standard first-line test, interpretation requires caution
Treatment of B12 deficiency typically includes oral supplements or injections
Under-dilution also concentrates any contaminants or degradation products
Improves Mood & Reduces Stress B12 contributes to serotonin production, improving mood and helping to manage stress
Rhonda Patrick adds: "NAD+ precursors like NMN increase levels, aiding DNA repair and energykey for anti-aging."[34] She suggests stacking with NNMT inhibitors for sustained effects
BPC 157 is not FDA approved to treat ulcerative colitis, Crohn's disease, IBS, or any other medical condition in humans
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