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The Fe 3 O 4 -PLGA-Ce 6 nanosystem, which dissociates in acidic TME, and the Fe 2+ -based metalorganic framework, which delivers Fe 2+ to cancer cells, can also promote the Fenton reaction and facilitate ferroptosis (Xu et al., 2020b
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Pemvidutide is also undergoing phase 2 studies as MASH treatment
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