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Semin Immunol (2016) 28(5):51424
Diabetes 42 , 7486 (2024)
Plus, it's free from added sugar
Across the SURPASS phase 3 programme versus placebo and active comparators, including semaglutide, tirzepatide has shown superior dose-dependent reductions in HbA1c levels up to 2.5% and body weight up to 13%, compared with all comparators [88-91]
Glucagon receptor activation, shared by both compounds, typically does not produce significant gastrointestinal side effects
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