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Another secondary endpoint was weight changes at 32 weeks

228, Dec

Regarding Diabetes mellitus management, the effect of metformin, a classic anti-diabetic drug, on epilepsy is controversial: on the one hand, studies have confirmed that it, as an AMPK agonist, activates thalamic AMP-activated protein kinase, thereby enhancing metabotropic GABAB receptor function and ultimately promoting absence epileptic seizures (95)

E., & Fielding, R

The research indicated that both GHS compounds increased body weight and total tibial and vertebral BMC measured by dual X-ray absorptiometry (DXA)

Protein quantification was carried out using the MaxLFQ algorithm as implemented in the DIA-NN R package ( and the number of peptides quantified in each protein group was counted as implemented in the DiannReportGenerator package ( 71