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For example, with semaglutide, begin at 0.25 mg weekly , increasing every four weeks

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Orlistat has traditionally been a first-line option due to its established safety profile and availability, though its modest efficacy (typically 3-5% additional weight loss beyond lifestyle intervention) and gastrointestinal side effects limit its appeal

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Treatment Protocols There are no existing treatment protocols for integrating weight loss peptides, particularly GLP-1 receptor agonists, into fertility care, which should outline clear steps regarding timing, monitoring, and safety

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