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All these trials were designed to evaluate the primary outcome of 3-MACE defined as cardiovascular death, nonfatal myocardial infarct, and nonfatal stroke, except for the ELIXA trial of exenatide ER, which included hospitalization for unstable angina as an additional component of the 4-MACE composite outcomes

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High-calorie, low-nutrient diets have become common, contributing to rising obesity rates (Galal 2003)

The latter approach overlooks the broad health benefits of exercise, pregnant or not

This often relates to reduced caloric intake rather than a direct drug effect

When a step-up changes the week, the comparison to the dose week before becomes obvious instead of vague