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The medication is administered through a convenient once-weekly subcutaneous injection, improving adherence and making it easier for our patients to incorporate into their routines
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Measurements of energy expenditure and locomotor activity HFD-induced obese C57BL/6J male mice were placed in individual small acryl calorimeter chambers with free access to HFD and water, and respiratory gas (O 2 and CO 2 ) were measured every 5 min for each individual mouse by indirect calorimetry system connected to mass spectrometer (Arco2000, ArcoSystem, Chiba, Japan)
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The goal is not necessarily the fastest possible weight loss
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