A KFF Health News data analysis of the FDAs Adverse Event Monitoring System found that medication errors made by providers or patients with popular weight loss drugs exploded from just over 2,000 reports in 2020 to over 25,000 in 2025
This is not directly caused by the medication but by metabolic changes during fat loss
It was made by replacing the chlorine atom in cyanine IR806 with disulfide pyridine dithioethylamine [91]
Women using oral contraceptives should be counseled about this potential interaction and may need to consider alternative or additional contraceptive methods, particularly during the initial weeks of treatment when gastric emptying effects may be most pronounced
In a February 2024 article for Managed Health Care Executive 3 , Lassen states, Our chief concern with these drugs right now is how do we best manage the waste, because theres a real potential if people in real-world practice are not staying on these medications, then they are not going to do anything but promote cost and temporary weight loss, he says
Mild injectionsite reactions (redness, itching, soreness) may occur with subcutaneous administration